Is Nitrous Oxide Sedation Safe?

January 4, 2026

Woman undergoing nitrous oxide sedation.

Nitrous oxide, often called “laughing gas,” is one of the most commonly used forms of dental sedation. If you or your child feel anxious about dental treatment, you may wonder whether nitrous oxide is a safe option. The good news is that nitrous oxide has a long history of safe and effective use in dentistry when administered properly.

What is Nitrous Oxide?

Nitrous oxide is a mild sedative gas mixed with oxygen and inhaled through a small mask placed over the nose. It helps patients feel calm, relaxed, and less aware of discomfort during dental procedures. Unlike deeper forms of sedation, nitrous oxide allows patients to remain awake and responsive throughout treatment.

Why Dentists Use Nitrous Oxide

Dentists commonly use nitrous oxide to help manage dental anxiety, gag reflexes, and mild discomfort. It’s suitable for both adults and children and can make routine procedures feel more manageable. Because the level of sedation can be adjusted at any time, dentists can tailor it to each patient’s comfort level.

Safety and Monitoring During Treatment

Nitrous oxide is considered very safe when administered by trained dental professionals. The gas is carefully mixed with oxygen and monitored throughout the appointment. Dentists follow strict guidelines to ensure patients receive the correct dosage. Because nitrous oxide is inhaled and not injected, it doesn’t put strain on the liver or kidneys.

Side Effects and Recovery Time

Side effects from nitrous oxide are usually mild and temporary. Some patients experience lightheadedness, tingling, or slight nausea, but these effects typically disappear quickly once the gas is turned off. One of the biggest advantages of nitrous oxide is its rapid recovery time—patients can usually drive themselves home and return to normal activities shortly after the appointment.

Who Should Avoid Nitrous Oxide?

While nitrous oxide is safe for most people, it may not be recommended for patients with certain respiratory conditions, nasal congestion, or specific medical concerns. Pregnant patients or those with vitamin B12 deficiencies should discuss options with their dentist. A thorough medical history helps determine whether nitrous oxide is appropriate.

Comparing Nitrous Oxide to Other Sedation Options

Compared to oral or IV sedation, nitrous oxide is the mildest form of sedation and carries fewer risks. It does not cause unconsciousness and can be stopped instantly if needed, making it a popular choice for patients seeking gentle anxiety relief.

When used correctly, nitrous oxide dental sedation is safe, effective, and widely trusted. If dental anxiety has kept you from seeking care, talking with your dentist about nitrous oxide may help make your next visit far more comfortable.

About the Author

Dr. Safraz Verjee has more than 15 years of experience in the dental field! He graduated from the NYU College of Dentistry before gaining real-world experience working as an associate dentist for a decade prior to opening his own practice in 2018. During his career, Dr. Verjee has taken hours of continuing education every year to learn new skills and stay current. If you need dental sedation to calm your anxious nerves, we can help. Book an appointment online or call our Pasadena office at (713) 943-9993.